Inhibitory effect of sulphated polysaccharide porphyran (isolated from Porphyra yezoensis) on RANKL-induced differentiation of RAW264.7 cells into osteoclasts
نویسندگان
چکیده
منابع مشابه
Inhibitory effect of sulphated polysaccharide porphyran on nitric oxide production in lipopolysaccharide-stimulated RAW264.7 macrophages.
Porphyran, extracted from an edible red alga (Porphyra yezoensis), is a sulphated polysaccharide with a wide variety of biological activities including anti-tumour, antioxidant and immuno-modulating activities. In this study, we examined the effect of porphyran on nitric oxide (NO) production in mouse macrophage cell line RAW264.7 cells. Although no significant activity of porphyran to induce N...
متن کاملAnti-cancer Effects of Polysaccharide and Phycocyanin from Porphyra Yezoensis
In this paper, phycocyanin and one component (PY-D2) in polysaccharide were obtained from Porphyra yezoensis to study for their potential anti-tumor effects. MTT proliferation assays showed that, at concentration of 500 mg/L for 72 h, PY-D2 treatment significantly inhibited the growth of four tumor cell lines, HO-8910, MCF-7, K562 and SMMC-7721, with the respective inhibition rates of 21.2%, 23...
متن کاملIsolation of porphyran-degrading marine microorganisms from the surface of red alga, Porphyra yezoensis.
Marine microorganisms degrading porphyran (POR) were found on the surface of thalli of Porphyra yezoensis. Fifteen crude microorganism groups softened and liquefied the surface of agar-rich plate medium. Among these, 11 microorganism groups degraded porphyran that consisted of sulfated polysaccharide in Porphyra yezoensis. Following isolation, 7 POR-degradable microorganisms were isolated from ...
متن کاملEffect of dietary porphyran from the red alga, Porphyra yezoensis, on glucose metabolism in diabetic KK-Ay mice.
Porphyran (POR) from the red alga Porphyra yezoensis is a water soluble dietary fiber. In this study, we investigated the effect of dietary POR on glucose metabolism in KK-Ay mice (a model for type 2 diabetes). Mice were divided into 4 groups and fed a diet containing 5% cellulose (control), POR, POR Arg or POR K. After 3 wk of feeding, plasma insulin levels and the calculated homeostasis model...
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ژورنال
عنوان ژورنال: Phytotherapy Research
سال: 2017
ISSN: 0951-418X
DOI: 10.1002/ptr.5988